Researchers at the Monell Chemical Senses Center found that common dietary sugars fructose and glucose, despite having the same amount of calories, communicate with the brain through different gut-brain pathways, a difference that may help shape our food and beverage preferences. In mice, the team identified a dedicated gut-brain signaling pathway through which fructose communicates with the brain and found that it is much less effective than glucose in turning down the activity of hunger-related neurons. Their findings were published June 10 in Neuron. “This work adds to our growing understanding of how modern diets, especially those high in fructose...