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Metabolic battle shapes deadly Candida infections

Metabolic battle shapes deadly Candida infections

As fungal infections kill an estimated 2 million people annually and antifungal resistance continues to rise, researchers have uncovered two nutrient-driven mechanisms that help explain how deadly Candida species evade immune defenses, pointing to a new generation of host-directed therapeutic approaches. Two studies by Monash University researchers, published in Nature Communications and Nature Microbiology, suggest nutrients can help determine the outcome of a biological tug-of-war between fungal pathogens and the human immune system.