Accurately tracking tiny heat changes offers a powerful way to monitor chemical reactions and living systems, but conventional calorimeters struggle with low throughput and slow analysis. This study introduces a high-throughput chip-based calorimetric platform that converts minute heat fluxes into electrical signals using an optimized thermoelectric sensor array. By integrating multiple sensing units on a single platform, the system enables parallel, real-time measurement of metabolic and reaction heat with high sensitivity. The approach allows rapid, label-free detection of biological activity and chemical processes, opening new possibilities for fast diagnostics and scalable thermal analysis in complex samples.
Measuring Life by Heat: A New Calorimetric Chip Enables Faster Antimicrobial Susceptibility Testing
