Anthony Colandrea passed for 275 yards and three touchdowns and ran for a fourth, Jamal Rule ran for 122 yards and scored three times and Nebraska pulled away from Ohio in the fourth quarter for a 49-21 victory. Colandrea led five straight touchdown drives to turn a close game into a blowout. Rule became the first Nebraska freshman running back to rush for 100 yards in an opener since 2004. Nebraska got all it could handle for three quarters from a Bobcats team looking to get the Mid-American Conference another Big Ten pelt two days after UMass knocked off Rutgers.